自1986年以來，Athens Research & Technology Inc.一直致力于人類蛋白質(zhì)的純化及相應(yīng)多克隆抗血清的開發(fā)。我們專注于提供高純度、高活性的人類蛋白質(zhì)產(chǎn)品，常規(guī)純化項目包括絲氨酸蛋白酶、蛋白酶抑制劑、中性粒細(xì)胞酶、載脂蛋白、脂蛋白、血小板蛋白、轉(zhuǎn)鐵蛋白、免疫球蛋白等。二十五年來，全球科研人員持續(xù)采購我們的研究試劑，這些產(chǎn)品在炎癥、冠心病、自身免疫疾病、癌癥、阿爾茨海默病等重大科學(xué)研究的文獻(xiàn)中屢被引用。
我們還能從動物血清和組織中分離蛋白質(zhì)。
國際診斷與制藥行業(yè)將我們的產(chǎn)品作為體外診斷試劑、免疫檢測試劑盒的核心組分，同時應(yīng)用于細(xì)胞培養(yǎng)基（包括干細(xì)胞培養(yǎng)基）。雅典研究與技術(shù)公司的蛋白質(zhì)也被生物治療藥物研發(fā)人員用于概念驗證實驗。
我們提供品質(zhì)可靠的產(chǎn)品與客戶服務(wù)——我們只銷售自主研發(fā)純化的產(chǎn)品。期待與您建立合作關(guān)系。
若您需要定制化研究服務(wù)，將能提供項目所需的特殊試劑。
貨號:16-16-012901
分子量（MW）：70,000
消光系數(shù)：0.703
通過20 mM雙亞氨基三（羥甲基）甲烷（Bis-Tris）緩沖液（pH 6.4，含200 mM NaCl）凍干制得。
儲存條件：≤ -20°C
人血漿α2抗纖溶蛋白（凝血因子）
可有效抑制纖溶酶原激活劑誘導(dǎo)的纖維蛋白凝塊溶解。血漿中濃度約為70微克/毫升。α-抗纖溶蛋白缺乏癥是一種罕見的凝血功能障礙，會導(dǎo)致纖溶活性不受限。此類患者可在術(shù)前接受治療性α2抗纖溶蛋白（A2AP），以預(yù)防術(shù)后出血。
純度：≥95%（通過SDS-聚丙烯酰胺凝膠電泳檢測）
活性：≥5.0 單位/毫克
本品由經(jīng)FDA批準(zhǔn)檢測顯示HBsAg、抗HCV、抗HBc陰性，且抗HIV 1/2陰性的血漿制備。
Athens Research & Technology產(chǎn)品為實驗室試劑，不可用于人體或作為藥物用途，僅限研究使用。
產(chǎn)品引用文獻(xiàn)：
Zimmerman, Thomas P., Valery Novokhatny, Shan Jiang, and James D. Colandene. "Reversibly inactivated acidified plasmin composition." U.S. Patent Application 13/761,684, filed February 7, 2013.
Singh S, Houng A, Reed GL.
Releasing the Brakes on the Fibrinolytic System in Pulmonary Emboli.
Circulation. 2017 Mar 14;135(11):1011-1020. doi: 0.1161/CIRCULATIONAHA.116.024421. Epub 2016 Dec 27
貨號:K060-H1
人髓過氧化物酶（MPO）酶聯(lián)免疫吸附試驗（EIA）試劑盒 特點：
用途——檢測多種基質(zhì)中的人MPO
樣本類型——血清、無血小板肝素血漿、唾液、尿液或組織培養(yǎng)液
樣本量/盒——40份（重復(fù)檢測）
靈敏度——0.068納克/毫升
穩(wěn)定性——液體試劑于4°C下穩(wěn)定保存
快速出結(jié)果——2.5小時內(nèi)完成
髓過氧化物酶（MPO）是一種四聚體含血紅素蛋白，主要由中性粒細(xì)胞大量產(chǎn)生，在其中發(fā)揮重要的抗微生物作用。當(dāng)粒細(xì)胞脫顆粒時，MPO會被釋放到細(xì)胞外空間。作為中性粒細(xì)胞“呼吸爆發(fā)"的一部分，它能通過過氧化氫（H?O?）和氯離子（Cl?）生成次氯酸（HOCl）。此外，MPO還能利用過氧化氫氧化酪氨酸生成酪氨酰自由基。次氯酸和酪氨酰自由基均具有細(xì)胞毒性，可有效殺滅細(xì)菌及其他病原體。遺傳性髓過氧化物酶缺乏癥會增加個體患免疫缺陷的風(fēng)險。
研究表明，MPO水平升高與冠狀動脈疾病相關(guān)。2003年有研究提出，MPO可能作為胸痛患者心肌梗死的敏感預(yù)測指標(biāo)。此后，大量文獻(xiàn)（已發(fā)表逾百篇）進(jìn)一步證實了MPO檢測在心臟病患者中的臨床價值。2010年的補充研究進(jìn)一步優(yōu)化了這一臨床應(yīng)用：通過聯(lián)合檢測MPO和C反應(yīng)蛋白（CRP），相較于單獨檢測CRP，可更精準(zhǔn)地預(yù)測死亡風(fēng)險。
參考文獻(xiàn)：
Zhang et al. (2001) Association between myeloperoxidase levels and risk of coronary artery disease; JAMA, 286 2135
Brennan et al. (2003) Prognostic value of myeloperoxidase in patients with chest pain; New Engl. J. Med., 349 1595
Heslop et al. (2010) Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography; J. Am. Coll. Of Cardiol. 55 1102
Athens研究與技術(shù)公司（ART）與Arbor檢測公司合作，推出了目前MPO EIA試劑盒。Arbor檢測公司的創(chuàng)始團(tuán)隊及頂尖科學(xué)家自1982年起便致力于研發(fā)高質(zhì)量檢測試劑盒。ART依托其30年在蛋白質(zhì)純化技術(shù)領(lǐng)域的經(jīng)驗，成功分離出高純度抗原；Arbor檢測團(tuán)隊在此基礎(chǔ)上，通過抗體配對設(shè)計、精細(xì)優(yōu)化及嚴(yán)格的質(zhì)量控制（其標(biāo)志性優(yōu)勢），最終開發(fā)出這款頂級酶聯(lián)免疫吸附試驗試劑盒。經(jīng)驗證，Athens研究與技術(shù)/Arbor檢測人MPO EIA試劑盒適用于血清、無血小板肝素血漿、唾液、尿液及組織培養(yǎng)液樣本，2.5小時內(nèi)即可完成檢測，靈敏度達(dá)0.068納克/毫升（注：原文此處可能存在筆誤，前文靈敏度為0.068 ng/mL，末段誤寫為0.68 ng/ml，翻譯保留原文數(shù)據(jù)）。該試劑盒可通過任一合作公司購買（Arbor檢測貨號：K060-H1；Athens研究與技術(shù)貨號：K060-H1）。
分子量（MW）：28,000
消光系數(shù)（Extinction Coefficient）：1.22
冷凍保存于10 mM NH?HCO?緩沖液（pH 7.4）中
儲存條件：≤-70°C
購買純化天然人載脂蛋白AI（ApoA1）（來源于人血漿）?？商峁┡坎少?。
高密度脂蛋白（HDL）中75%的載脂蛋白A為Apo AI。Apo AI水平與冠心病風(fēng)險呈負(fù)相關(guān)。此外，Apo AI被認(rèn)為可激活卵磷脂膽固醇?；D(zhuǎn)移酶（LCAT）。正常血漿中，Apo AI水平范圍為90-130 mg/100 mL。
純度：通過SDS-PAGE檢測≥95%
本產(chǎn)品由經(jīng)FDA批準(zhǔn)方法檢測為陰性的血漿制備（乙肝表面抗原[HBsAg]、丙肝抗體[anti-HCV]、乙肝核心抗體[anti-HBc]無反應(yīng)；人類免疫缺陷病毒1型/2型抗體[anti-HIV 1 & 2]陰性）。
Athens Research & Technology產(chǎn)品為實驗室試劑，不可用于人體或任何藥物用途，僅限研究使用。
產(chǎn)品引用文獻(xiàn)： Soffientini, Ugo, et al. "Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis." Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 1841.10 (2014): 1372-1382.
Soffientini U, Dolan S, Graham A.
Cytosolic lipid trafficking proteins STARD4 and STARD5 modulate hepatic neutral lipid metabolism: implications for diabetic dyslipidaemia and steatosis.
Journal of Diabetes and Metabolism, Volume 6, Issue number 588. DOI: 10.4172/2155-6156.1000558.
Winford, Sidney, Moriah Tobin, and Eitan Gross. "Surface-induced assembly of apolipoprotein AI: Implications for symmetry-driven non-cooperative clustering."Journal of Crystal Growth 343, no. 1 (2012): 38-44.
Konno, Shunichi, Masami Tanio, Itsuko Ishii, Kazuhiko Machida, Fumiaki Matsumoto, Kaneshige Satoh, Masayuki Aso, and Yasushi Saito. "Ceiling culture-derived proliferative adipocytes are a possible delivery vehicle for enzyme replacement therapy in lecithin: cholesterol acyltransferase deficiency." Open Gene Therapy Journal 4 (2011): 1-10.
Scharadin TM, et al.
Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.
PLOS One, 2017 Jun 6;12(6).
Prathipati P, Zhu J, Dong X.
Development of novel HDL-mimicking α-tocopherol-coated nanoparticles to encapsulate nerve growth factor and evaluation of biodistribution.
Eur J Pharm Biopharm. 2016 Nov;108:126-135. doi: 10.1016/j.ejpb.2016.08.005. Epub 2016 Aug 12.
技術(shù)深度與廣度兼?zhèn)洌焊采w抗體開發(fā)（多克隆/單克隆/重組抗體）、功能試劑盒（ELISA/Western Blot/流式檢測）、細(xì)胞培養(yǎng)（原代細(xì)胞/干細(xì)胞/類器官培養(yǎng)基）三大核心技術(shù)方向，可滿足從基礎(chǔ)研究到轉(zhuǎn)化醫(yī)學(xué)的全流程需求。
嚴(yán)格的品控體系：所有產(chǎn)品均經(jīng)過“原料溯源-工藝驗證-性能測試-批次留樣"四步質(zhì)控，關(guān)鍵指標(biāo)（如抗體親和力、試劑盒靈敏度）的批次間差異率≤5%，確保實驗結(jié)果可重復(fù)。
定制化服務(wù)響應(yīng)快：針對客戶的個性化需求（如新型抗原抗體開發(fā)、特殊物種細(xì)胞培養(yǎng)基優(yōu)化），提供“需求溝通-方案設(shè)計-樣品測試-量產(chǎn)交付"的全周期支持，平均定制周期較行業(yè)縮短30%。
全球化的服務(wù)網(wǎng)絡(luò)：在美國、歐洲及亞太地區(qū)設(shè)立倉儲中心，支持48小時內(nèi)緊急訂單發(fā)貨；配備專業(yè)的技術(shù)支持團(tuán)隊（含中文服務(wù)），為全球客戶提供7×12小時技術(shù)咨詢。
高校/科研院所實驗室：為基礎(chǔ)醫(yī)學(xué)、生物學(xué)、藥學(xué)等領(lǐng)域的師生提供高性價比的研究工具，支持論文發(fā)表與課題申報。
生物醫(yī)藥企業(yè)研發(fā)部：為新藥靶點驗證、藥效評價、臨床前研究提供定制化試劑（如疾病模型動物用抗體、細(xì)胞功能檢測試劑盒）。
診斷試劑開發(fā)商：提供高特異性抗原/抗體原料，用于傳染病、腫瘤標(biāo)志物等體外診斷試劑盒的開發(fā)。
類器官/器官芯片研究團(tuán)隊：定制化培養(yǎng)基與基質(zhì)膠產(chǎn)品，支持干細(xì)胞衍生類器官的高效培養(yǎng)與功能維持。
Q1：AR的抗體在跨物種檢測中表現(xiàn)如何？
A：AR抗體開發(fā)時均經(jīng)過多物種同源性分析，優(yōu)先選擇保守表位設(shè)計抗原，確保在人、小鼠、大鼠等常見物種中具有良好的交叉反應(yīng)性。若需特殊物種（如兔、猴）檢測，可提供定制化抗原表位設(shè)計服務(wù)。
Q2：定制化產(chǎn)品的交付周期需要多久？
A：常規(guī)定制（如抗體亞型轉(zhuǎn)換）約4-6周；復(fù)雜項目（如全新抗原開發(fā)+抗體篩選）約12-16周，具體時間根據(jù)需求復(fù)雜度評估后會與客戶確認(rèn)。
Q3：產(chǎn)品出現(xiàn)質(zhì)量問題如何解決？
A：AR提供“30天無理由退換"服務(wù)（需保留完整包裝與使用記錄）。若因產(chǎn)品質(zhì)量問題導(dǎo)致實驗失敗，經(jīng)技術(shù)驗證后可免費補發(fā)或退款，并安排專人跟進(jìn)解決。
Q4：是否支持小批量采購？
A：是的，AR提供毫克級抗體、微升級試劑盒及小規(guī)格培養(yǎng)基的采購選項，起訂量可根據(jù)客戶需求協(xié)商調(diào)整，降低中小實驗室的采購成本。
貨號 | 品名 | 規(guī)格 | 品牌 |
16-16-090707-1M | Immunoglobulin G1, Human Myeloma Plasma | 1mg | Athens Research |
16-14-051200-100ug | Elastase, Human Neutrophil | 100ug | Athens Research |
16-16-090707-2M-1MG | Immunoglobulin G2 Human Myeloma Plasma | 1mg | Athens Research |
12-16-121601-1mg | Lipoprotein (a), Human Plasma | 1mg | Athens Research |
16-16-032001-LEL-1gram | Transferrin (HOLO), Human Plasma, Tissue Culture Grade | 1gram | Athens Research |
16-16-090705-100ug | Immunoglobulin E, Human Plasma | 100ug | Athens Research |
12-16-121601-100ug | Lipoprotein (a), Human Plasma | 100ug | Athens Research |
16-14-130000-1mg | Myeloperoxidase, Human Neutrophil | 1mg | Athens Research |
16-16-090701-1M-10mg | Immunoglobulin A1, Human Myeloma Plasma | 10mg | Athens Research |
16-16-161200-1mg | Plasminogen, Human Plasma | 1mg | Athens Research |
16-16-011609-5mg | Alpha 1 Antitrypsin, Human Plasma | 5mg | Athens Research |
16-16-120303-1mg | Apolipoprotein CIII, Human Plasma | 1mg | Athens Research |
16-16-161213-L-1mg | Plasmin, Human Plasma (lyophilized) | 1mg | Athens Research |
16-16-090701-1M-1mg | Immunoglobulin A1, Human Myeloma Plasma | 1mg | Athens Research |
16-16-090701-1M-5mg | Immunoglobulin A1, Human Myeloma Plasma | 5mg | Athens Research |
16-16-090707-1M-10mg | Immunoglobulin G1, Human Myeloma Plasma | 10mg | Athens Research |
12-16-120412-OX-1mg | Lipoproteins, Oxidized, Low Density, Human Plasma | 1mg | Athens Research |
16-14-012621-1mg | Azurocidin, Human Neutrophil | 1mg | Athens Research |
16-14-130000作廢 | Myeloperoxidase, Human Neutrophil | 100ug | Athens Research |
16-16-090713-10mg | Immunoglobulin M, Human Plasma | 10mg | Athens Research |
16-16-090713-M-1MG | Immunoglobulin M (IgM) Human Myeloma Plasma | 1mg | Athens Research |
16-16-090713-Mfc5u-1mg | Immunoglobulin M, Fc5mu, Human Plasma | 1mg | Athens Research |
16-20-201319 | Thrombospondin, Human Platelet | 25ug | Athens Research |
16-05-030112-P-1mg | Calpain-1, Porcine Erythrocytes | 1 mg | Athens Research |
16-14-030107-100ug | Cathepsin G, Human Neutrophil | 100ug | Athens Research |
16-14-051200-1mg | Elastase, Human Neutrophil | 1mg | Athens Research |
16-14-130000-100ug | Myeloperoxidase, Human Neutrophil | 100ug | Athens Research |
16-14-161820-25ug | Proteinase 3 (PR3), Human Neutrophil | 25ug | Athens Research |
16-16-030402-100ug | C4b-Binding Protein, Human Plasma | 100ug | Athens Research |
16-16-030402-1mg | C4b-Binding Protein, Human Plasma | 1mg | Athens Research |
16-16-081907-1mg | Alpha 2 HS Glycoprotein, Human Plasma | 1mg | Athens Research |
16-16-090701-10mg | Immunoglobulin A1 (IgA1), Human Myeloma Plasma | 10mg | Athens Research |
16-16-090701-2M-1mg | Immunoglobulin A2, Human Plasma | 1mg | Athens Research |
16-16-090707-1-1mg | Immunoglobulin G1, Human Normal Plasma | 1mg | Athens Research |
12-16-030825-1mg | Chylomicrons, Human Plasma | 1mg | Athens Research |
16-05-030112-P-100ug | Calpain-1, Porcine Erythrocytes | 100 ug | Athens Research |
16-12-030102-25ug | Cathepsin B, Human Liver | 25ug | Athens Research |
16-12-030102-50ug | Cathepsin B, Human Liver | 50ug | Athens Research |
16-13-090701-10mg | Secretory IgA, Human Colostrum | 10mg | Athens Research |
16-13-090701-5mg | Secretory IgA, Human Colostrum | 5mg | Athens Research |
16-14-012621-100ug | Azurocidin, Human Neutrophil | 100ug | Athens Research |
16-14-161820-100ug | Proteinase 3, Human Neutrophil | 100ug | Athens Research |
16-16-010700-10mg | Alpha 1 Acid Glycoprotein (A1AGP), Human Plasma | 10mg | Athens Research |
16-16-011609-1mg | Alpha 1 Antitrypsin, Human Plasma | 1mg | Athens Research |
16-16-012020-1mg | Antithrombin III, Human Plasma | 1mg | Athens Research |
16-16-012901-100UG | Alpha 2 Antiplasmin, Human Plasma | 100ug | Athens Research |
16-16-032001-1gram | Transferrin (HOLO), Human Plasma | 1 gram | Athens Research |
16-16-032001-CM-1mg | Transferrin, Cynomolgus Monkey ** | 1mg | Athens Research |
16-16-032001-CM-5mg | Transferrin, Cynomolgus Monkey | 5 mg | Athens Research |
16-16-080116-1/1-1mg | Haptoglobin, Phenotype 1-1, Human Plasma | 1mg | Athens Research |
16-16-080116-2/2-1mg | Haptoglobin, Phenotype 2-2, Human Plasma | 1mg | Athens Research |
16-16-080116-5mg | Haptoglobin, Human Plasma, Mixed Type | 5mg | Athens Research |
16-16-090109-100ug | Inter Alpha Inhibitor Proteins (IaIp), Human Plasma | 100ug | Athens Research |
16-16-090707-1M-5mg | Immunoglobulin G1, Human Myeloma Plasma | 5mg | Athens Research |
16-16-090707-FC-1mg | Immunoglobulin G, FC Fragment, Human Plasma | 1mg | Athens Research |
16-16-090713-1mg | Immunoglobulin M, Human Plasma | 1mg | Athens Research |
16-16-110112-RAT-50ug | Kallikrein, Rat Plasma | 50ug | Athens Research |
16-16-120101-1mg | Apolipoprotein AI, Human Plasma | 1mg | Athens Research |
16-16-120500-1mg | Apolipoprotein E, Human Plasma | 1mg | Athens Research |
16-16-120500-50ug | Apolipoprotein E, Human Plasma | 50ug | Athens Research |
16-16-161801-1mg | Prealbumin, Human Plasma (Transthyretin) | 1mg | Athens Research |
01-05-030000-1ML | Anti-Catalase Polyclonal Ab, Human Erthrocyte | 1ml | Athens Research |
12-16-120412-5mg | Lipoproteins, Low Density, Human Plasma | 5mg | Athens Research |
12-16-221204-5mg | Lipoproteins, Very Low Density, Human Plasma | 5mg | Athens Research |
16-05-030000-1mg | Catalase, Human Erythrocyte (50 KU per mg) | 1mg | Athens Research |
16-12-030104-100ug | Cathepsin D, Human Liver | 100ug | Athens Research |
16-12-030104-25ug | Cathepsin D, Human Liver | 25ug | Athens Research |
16-12-030112-25ug | Cathepsin L, Human Liver | 25ug | Athens Research |
16-13-090701-1mg | Secretory IgA, Human Colostrum | 1mg | Athens Research |
16-13-A20103 | Apolactoferrin, Human Milk | 5mg | Athens Research |
16-14-030107-50ug | Cathepsin G, Human Neutrophil | 50ug | Athens Research |
16-15-160518-100ug | Eosinophil Peroxidase, Human Eosinophils | 100ug | Athens Research |
16-16-011202-CM-10mg | Albumin, Cynomolgus Monkey ** | 10mg | Athens Research |
16-16-012013-1mg | Alpha 2 Macroglobulin, Human Plasma | 1mg | Athens Research |
16-16-012400-1mg | Alpha 1 Antichymotrypsin, Human Plasma | 1mg | Athens Research |
16-16-012901-1MG | Alpha 2 Antiplasmin, Human Plasma | 1mg | Athens Research |
16-16-012901-500UG | Alpha 2 Antiplasmin, Human Plasma | 500ug | Athens Research |
16-16-030518-1mg | Ceruloplasmin, Human Plasma | 1mg | Athens Research |
16-16-080116-1mg | Haptoglobin, Human Plasma, Mixed Type | 1mg | Athens Research |
16-16-080513-LEL | Hemopexin, Low Endotoxin Level, Human Plasma | 1mg | Athens Research |
16-16-090109-1mg | Inter Alpha Inhibitor Proteins (IaIp), Human Plasma | 1mg | Athens Research |
16-16-090109-25ug | Inter Alpha Inhibitor Proteins (IaIp), Human Plasma | 25ug | Athens Research |
16-16-090701-1mg | Immunoglobulin A, Human Plasma | 1mg | Athens Research |
16-16-090705 | Immunoglobulin E, Human Plasma 1mg | 1mg | Athens Research |
16-16-090705-M-Lambda-100ug | Immunoglobulin E, Human Myeloma Plasma, Lambda | 100ug | Athens Research |
16-16-090707 | 人免疫球蛋白 | 毫克 | Athens Research |
16-16-090707-2M-10mg | Immunoglobulin G2, Human Myeloma Plasma | 10mg | Athens Research |
16-16-090707-2M-5mg | Immunoglobulin G2, Human Myeloma Plasma | 5mg | Athens Research |
16-16-090707-4M-1mg | Immunoglobulin G4, Human Myeloma Plasma | 1mg | Athens Research |
16-16-090707-Fc-10mg | Immunoglobulin G, Fc Fragment, Human Plasma | 10mg | Athens Research |
16-16-090713-BULK | Immunoglobulin M, Human Plasma | 1g | Athens Research |
16-16-110112-50ug | Kallikrein, Human Plasma (frozen) | 50ug | Athens Research |
16-16-110112-CM | Kallikrein, Cynomolgus Monkey Plasma | 50ug | Athens Research |
16-16-110914-L-1mg | Kininogen, Low Molecular Weight, Human Plasma | 1mg | Athens Research |
16-16-120101-500ug | Apolipoprotein AI, Human Plasma | 500ug | Athens Research |
16-16-120101-LEL-1mg | Apolipoprotein AI, Human Plasma, LEL | 1mg | Athens Research |
16-16-120200-500ug | Apolipoprotein B, Human Plasma | 500ug | Athens Research |
16-16-180603-250ul | Rheumatoid Factor (IgM), Human Plasma | 250ul | Athens Research |
16-16-A32001-100mg | APO Transferrin, Human Plasma | 100mg | Athens Research |
16-16-A32001-1gram | APO Transferrin, Human Plasma | 1gram | Athens Research |
